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2-CYCLOHEXENYL CYCLOHEXANONE.

Optional CAS 1502-22-3 / PERFUMING

A synthetic aromatic compound belonging to the alkyl cyclic ketones family, primarily utilized as a fragrance component and solvent in cosmetic formulations. This volatile ketone provides olfactory enhancement but offers no proven physiological benefits for skin health or anti-aging. While generally well-tolerated at low concentrations, its primary value lies in sensory experience rather than functional skincare improvement.

perfuming solvent

Science

Functions exclusively as a fragrance molecule that interacts with olfactory receptors and serves as a solvent system component. Does not engage with skin cellular processes or provide bioactive mechanisms for barrier repair, collagen synthesis, or other physiological improvements.


Research

Medium confidence
Effective range 0.1–1%
Optimal

0.5%

Key findings

  1. 01 Demonstrated non-sensitizing properties within alkyl cyclic ketones fragrance group, meeting dermal sensitization threshold criteria

Transparency

Commonly dusted
Min. effective
0.05%
Red flag below
1.5%

Frequently used in minimal concentrations for fragrance masking or enhancement, though concentrations above 1.5% may indicate formulation issues or potential irritancy concerns


The Formula

Solubility
Oil
Optimal pH 4 – 8
0 7 14

Stability

Exhibits oxidation susceptibility with potential color change from colorless to pale yellow over time. High volatility with low flash point at 44°C requires careful storage and handling protocols.

Conflicts

  • Strong oxidizing agents
  • Nitric acid
  • Certain plastic packaging materials

Safety

CIR Status
Not reviewed by CIR; regulated under IFRA standards
Max tested
1%
Sensitization risk Low

RIFM assessment confirms safety below Threshold of Toxicological Concern for Cramer Class II materials. Neat application shows irritancy potential, but dilutions below 12% demonstrate minimal irritation risk.


Your Skin

Yes Normal
Yes Dry
Yes Oily
No Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Optional

A functional fragrance ingredient with established safety profile but no skincare benefits beyond sensory enhancement.


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References