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Moumoujus

2-CHLORO-6-ETHYLAMINO-4-NITROPHENOL.

Questionable CAS 131657-78-8 / HAIR DYEING

A nitro-aromatic compound primarily utilized as a direct hair colorant that imparts yellow-orange hues without requiring chemical bonding to keratin. This synthetic dye penetrates hair cuticles through its chromophore structure, offering predictable coloring effects in both oxidative and non-oxidative formulations. While developed for hair applications, its presence in skincare formulations remains limited due to sensitization concerns.

Summary

Hair coloring Direct dye

Science

Mechanism of Action

Functions through electronic transitions of its nitro-aromatic chromophore to produce color, penetrating hair cuticles or adhering to surfaces without forming chemical bonds with keratin proteins

Research

Clinical Evidence

High confidence
Effective range 1.5–3%
Optimal

3%

Key findings

  1. 01 Maximum safe concentration in oxidative hair formulations when mixed with hydrogen peroxide
  2. 02 Authorized maximum in semi-permanent non-oxidative hair products

Transparency

Dusting Analysis

Not commonly dusted

Primarily used as functional hair colorant at regulated concentrations rather than cosmetic dusting ingredient

The Formula

Formulation

Solubility
Both
Optimal pH 6 – 9
0 7 14

Stability

Maintains stability exceeding 5 years under dry, dark storage conditions. Demonstrates 97%+ recovery after 7 days in aqueous systems at pH 5.8 and remains stable in hydrogen peroxide environments during dyeing processes.

Conflicts

  • Strong oxidizing agents (extended exposure)
  • Nitrosating compounds (nitrosamine formation risk)

Safety

Safety Profile

CIR Status
Not reviewed
Max tested
3%
Sensitization risk High

EU Scientific Committee considers it safe for hair applications up to specified concentrations but classifies as skin sensitizer. No CIR assessment available for this specific derivative.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
No Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Verdict

Questionable

Effective hair colorant with regulatory approval but high sensitization risk limits skincare applications.

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