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Moumoujus

2-AMINO-6-CHLORO-4-NITROPHENOL.

Optional CAS 6358-09-4 / HAIR DYEING

A specialized synthetic colorant primarily used in hair dyeing formulations that functions as both a direct dye and oxidative colorant component. This aromatic compound features amino, chloro, and nitro substituents that enable light absorption to produce yellow-orange coloration in hair products. Despite its hair-focused applications, it demonstrates excellent safety profiles with minimal skin penetration at less than 0.25% absorption.

Summary

hair dyeing colorant

Science

Mechanism of Action

Functions through direct penetration into hair shafts where its substituted aromatic structure absorbs specific light wavelengths to create color deposits, while maintaining extremely low dermal permeability due to its molecular characteristics

Research

Clinical Evidence

High confidence
Effective range 0.5–2%
Optimal

2%

Key findings

  1. 01 OECD 404 skin irritation study at 0.5% concentration showed non-irritating properties
  2. 02 CIR Expert Panel assessment confirmed 2.0% solutions are non-irritating under occlusive conditions
  3. 03 OECD 405 eye irritation studies at 2% demonstrated no ocular irritation potential

Transparency

Dusting Analysis

Not commonly dusted
Min. effective
2%
Red flag below
2.1%

Regulatory limits cap usage at 2.0% for non-oxidative formulations and 1.0% for oxidative systems, making higher concentrations regulatory red flags

The Formula

Formulation

Solubility
Water
Optimal pH 6 – 9.5
0 7 14

Stability

Maintains stability in cream formulations at pH 9.5 for minimum 4 weeks at 25°C, remains stable under oxidative conditions when combined with hydrogen peroxide

Synergies

  • Hydrogen peroxide (for oxidative dyeing systems)

Conflicts

  • Strong oxidizing agents (except intentional oxidative dyeing)
  • Strong acids

Safety

Safety Profile

CIR Status
Safe as used
Max tested
2%
Sensitization risk Low

EU restrictions limit to 2.0% in non-oxidative products and 1.0% when mixed with hydrogen peroxide for oxidative formulations

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
No Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Verdict

Optional

A well-validated hair colorant with excellent safety data but limited skincare applications beyond specialized coloring formulations.

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