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2,6-DIHYDROXYETHYLAMINOTOLUENE.

Insufficient Data CAS 149330-25-6 / HAIR DYEING

A secondary intermediate compound primarily utilized in oxidative hair coloring systems to create permanent color results. This water-soluble amine functions as a coupler that reacts with primary dye precursors under oxidizing conditions to generate stable color molecules within the hair shaft.

Hair dyeing Color coupling

Science

Functions as a coupler in oxidative dyeing by reacting with primary intermediates such as p-phenylenediamine in the presence of hydrogen peroxide, forming large chromophore molecules that create permanent coloration


Research

High confidence
Effective range ≤1%
Optimal

1%

Key findings

  1. 01 SCCS safety evaluation at 1.0% concentration for oxidative hair dye applications (SCCS/1563/15)
  2. 02 OECD 404 acute dermal irritation study showing non-irritating properties at 100% concentration

Transparency

Not commonly dusted

Primarily used in hair coloring applications rather than skincare formulations


The Formula

Solubility
Water
Optimal pH 2 – 11
0 7 14

Stability

Demonstrates high stability in aqueous suspensions for minimum 24 hours at ambient temperature with solubility of 39.9 g/L at pH 8.2

Synergies

  • Primary dye intermediates
  • Hydrogen peroxide oxidizing systems

Conflicts

  • Nitrosating agents
  • Nitrite-containing materials

Safety

CIR Status
Not reviewed
Max tested
1%
Sensitization risk Low

SCCS approved for 1% maximum on-head concentration with strict prohibition against nitrosating agents due to nitrosamine formation risk; maximum allowable nitrosamine content 50 μg/kg


Your Skin

No Normal
No Dry
No Oily
No Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Insufficient Data

Specialized hair dyeing ingredient with limited skincare applications and unknown compatibility across skin types.


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