Science
Mechanism of Action
Functions exclusively through sensory enhancement by providing pleasant fragrance notes and masking undesirable base odors in formulations, with no established biological activity for skin health improvement.
Research
Clinical Evidence
Low confidenceN/A
Key findings
- 01 OECD TG 428 skin absorption study at 1% showed 3.13% permeation (unoccluded) and 11.1% (occluded) over 24 hours
- 02 RIFM safety evaluation at 0.06% concentration in body spray applications confirmed systemic safety parameters
Transparency
Dusting Analysis
As a fragrance component with established concentration limits, dusting is not a common practice for this ingredient
The Formula
Formulation
Stability
Acetal structure makes it vulnerable to hydrolytic breakdown in acidic conditions, converting to acetophenone and neopentyl glycol components
Conflicts
- Acidic formulations below pH 6.0
- Strong oxidizing agents
Safety
Safety Profile
RIFM Expert Panel concluded safe as used in fragrance applications. ECHA classification includes Skin Sensitizer Category 1 and Eye Irritant Category 2 designations.
Your Skin
Skin Compatibility
Our Assessment
Verdict
A functional fragrance ingredient with high sensitization potential that serves sensory rather than therapeutic purposes in skincare.
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References
Sources