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2,4-DIAMINOPHENOXYETHANOL SULFATE.

Avoid CAS 70643-20-8 / HAIR DYEING

A specialized chemical compound primarily designed as a color coupler in permanent hair dyeing systems. This ingredient creates durable pigment molecules through oxidative reactions but faces strict regulatory limitations for skincare applications due to its sensitization potential.

hair dyeing color coupling

Science

Functions as a reactive intermediate that combines with oxidative precursors in the presence of hydrogen peroxide to generate large, stable pigment molecules that resist washing


Research

Medium confidence
Effective range ≤2%
Optimal

N/A

Key findings

  1. 01 European safety assessment confirmed maximum safe concentration for hair dye applications with EC3 sensitization value of 3.2%

Transparency

Not commonly dusted

Not applicable to skincare formulations due to regulatory restrictions and specialized hair dye function


The Formula

Solubility
Water
Optimal pH 1.9 – 2.1
0 7 14

Stability

Demonstrates high water solubility (98.2 g/L at pH 2.1) with 6-hour room temperature stability, though optimal preservation requires refrigeration at 4°C under inert atmosphere

Conflicts

  • Hydrogen peroxide
  • Strong oxidizing agents
  • Light exposure
  • Oxygen/air exposure

Safety

CIR Status
Safe with restrictions
Max tested
2%
Sensitization risk Moderate

Approved exclusively for hair coloring applications with mandatory patch testing requirements. Prohibited in non-hair cosmetic products including skincare and eye makeup in the US without specific color additive approval


Your Skin

No Normal
No Dry
No Oily
No Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Avoid

Unsuitable for precision skincare due to regulatory restrictions and specialized hair dye function with moderate sensitization risk.


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