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2,4-DIAMINOPHENOL HCL.

Avoid CAS 137-09-7 / HAIR DYEING

A specialized chemical compound primarily used as a coupler in oxidative hair coloring systems and professional eyelash/eyebrow tinting. This ingredient undergoes chemical transformation in the presence of oxidizing agents to create permanent color molecules within hair structures. It is not intended for general skincare applications due to its specific dyeing function and moderate irritation profile.

Hair dyeing coupler Color formation catalyst

Science

Functions as a reactive precursor that combines with primary intermediates in oxidative environments to form large, stable pigment molecules that become permanently embedded in hair shafts or surface structures


Research

High confidence
Effective range 0.2–2%
Optimal

2%

Key findings

  1. 01 Dermal penetration study demonstrated 0.41% absorption in oxidative formulations versus 1.68% in non-oxidative systems

Transparency

Not commonly dusted

Not applicable to skincare formulations as this ingredient is restricted to hair and professional eye area coloring products


The Formula

Solubility
Water
Optimal pH 1 – 2
0 7 14

Stability

Extremely unstable in aqueous solutions with only 6-hour stability at room temperature; requires refrigerated storage (4°C) and protection from light and oxygen for extended stability up to 9 days

Synergies

  • Hydrogen peroxide
  • Primary hair dye intermediates

Conflicts

  • Strong oxidizing agents
  • Strong acids
  • Heat exposure
  • Light exposure

Safety

CIR Status
Safe with restrictions
Max tested
2%
Sensitization risk Moderate

Approved for hair dyeing applications up to 2.0% concentration post-mixing; recognized as skin and ocular irritant; EU restrictions limit use to hair and professional eye area treatments only


Your Skin

No Normal
No Dry
No Oily
No Sensitive
Irritancy Moderate
Comedogenicity Unknown

Our Assessment

Avoid

Specialized hair coloring ingredient with moderate irritation potential and no established skincare benefits - inappropriate for facial or body skincare formulations.


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