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2,4-DIAMINO-5-METHYLPHENETOLE HCL.

Avoid CAS 113715-25-6 / HAIR DYEING

A specialized oxidative coupler primarily designed for permanent hair coloring applications. This aromatic amine salt creates stable color molecules through chemical coupling reactions in highly alkaline environments, making it unsuitable for conventional skincare formulations.

hair dyeing

Science

Functions as an m-diamine coupler that reacts with oxidizing agents and primary intermediates to form large, permanent pigment molecules within hair shafts through chemical coupling reactions


Research

Medium confidence
Effective range 0.56–2.4%
Optimal

N/A

Key findings

  1. 01 Safety evaluation in oxidative hair dye formulations showed no significant skin irritation at typical concentrations, with identification as potential skin sensitizer

Transparency

Not commonly dusted

Restricted to hair dye applications with specific regulatory limitations, making dusting practices irrelevant for skincare contexts


The Formula

Solubility
Water
Optimal pH 9 – 11
0 7 14

Stability

Maintains stability exclusively in alkaline conditions required for hair dyeing; becomes ineffective in acidic skincare environments and shows sensitivity to light and air exposure

Conflicts

  • Strong oxidizing agents
  • Acidic environments
  • Formaldehyde donors

Safety

CIR Status
Safe with restrictions
Max tested
2.4%
Sensitization risk Moderate

Restricted exclusively to oxidative hair dye applications by CIR and European regulations, with 2% maximum on-head concentration for permanent hair dyes


Your Skin

No Normal
No Dry
No Oily
No Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Avoid

Exclusively designed for hair coloring with no skincare applications due to regulatory restrictions and pH incompatibility.


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