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Moumoujus

2,3-NAPHTHALENEDIOL.

Insufficient Data CAS 92-44-4 / HAIR DYEING

A naphthalene derivative primarily developed as a coupling agent for oxidative hair dyes, with emerging research exploring its potential as an antioxidant and tyrosinase inhibitor in skincare applications. While it showed non-irritant properties at 0.1% concentration in patch testing, regulatory authorities have deemed current safety data insufficient for general cosmetic use.

Summary

Antioxidant Tyrosinase inhibitor Coupling agent

Science

Mechanism of Action

Functions through oxidative coupling reactions in hair dye systems, where it reacts with primary intermediates to form permanent pigment molecules. In skincare research, it demonstrates potential antioxidant activity and may inhibit tyrosinase enzyme activity, which could theoretically help regulate melanin production.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

0.1%

Key findings

  1. 01 Demonstrated non-irritant status in human patch testing

Transparency

Dusting Analysis

Not commonly dusted

Primarily used in hair care formulations rather than skincare products, making dusting practices irrelevant for this ingredient.

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Stability

Exhibits sensitivity to oxidation and air exposure, requiring stabilized formulations or specialized packaging to prevent degradation

Conflicts

  • Strong oxidizing agents
  • Hydrogen peroxide

Safety

Safety Profile

CIR Status
Insufficient data
Sensitization risk Unknown

CIR Expert Panel concluded insufficient safety data for cosmetic use. Prohibited in EU hair dye formulations under Annex II regulations.

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
No Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Insufficient Data

While showing promise as an antioxidant with non-irritant properties at low concentrations, insufficient safety data limits its current viability for precision skincare applications.

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