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2,3-DIAMINODIHYDROPYRAZOLO PYRAZOLONE DIMETHOSULFONATE.

Questionable CAS 857035-95-1 / HAIR DYEING

An oxidative dye precursor primarily developed for hair coloring applications that generates intense pigmentation through chemical condensation reactions. While occasionally found in certain radiance-enhancing skincare products, its primary function remains pigment development rather than traditional skincare benefits.

oxidative dye precursor pigmentation enhancer

Science

Functions as a primary intermediate that undergoes oxidative condensation with coupling agents in the presence of hydrogen peroxide under alkaline conditions, forming large chromophore molecules that create visible color enhancement on skin surfaces.


Research

Medium confidence
Effective range 0.3–2%
Optimal

N/A

Key findings

  1. 01 SCCS safety evaluation at 2.0% maximum concentration for oxidative applications
  2. 02 Patent formulation studies demonstrating stable pigmentation at 0.3% when combined with complementary precursors

Transparency

Not commonly dusted

Specialized ingredient with limited cosmetic applications outside of hair dye formulations; not commonly used for marketing enhancement in skincare


The Formula

Solubility
Water
Optimal pH 6 – 12
0 7 14

Stability

Exceptionally water-soluble (>603 g/L) but requires careful handling due to oxidative sensitivity. Maintains stability for 6 hours at ambient temperature or 9 days refrigerated when protected from light and oxygen exposure.

Synergies

  • 2-amino-3-hydroxypyridine
  • oxidative coupling agents

Conflicts

  • hydrogen peroxide
  • oxidizing agents
  • light exposure
  • atmospheric oxygen

Safety

CIR Status
Not reviewed
Max tested
2%
Sensitization risk High

SCCS classification as strong skin sensitizer with 2.0% maximum restriction for hair dye applications. Safety profile for leave-on skincare applications remains unestablished through formal CIR assessment.



Our Assessment

Questionable

Specialized hair dye intermediate with high sensitization potential and limited established safety data for skincare applications.


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