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2,3,6-TRIMETHYLPHENOL.

Avoid CAS 2416-94-6 / PERFUMING

A synthetic phenolic compound that serves as an antioxidant and antimicrobial preservative booster in skincare formulations. This crystalline ingredient helps prevent oxidative degradation while providing secondary preservation benefits through its fungicidal properties.

antioxidant preservative booster antimicrobial

Science

Functions as a free radical scavenger that intercepts reactive oxygen species to prevent lipid peroxidation and formulation degradation. Additionally provides antimicrobial activity against specific fungal strains, enhancing overall product stability and shelf life.


Research

Low confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

Rarely used in cosmetic formulations; primarily appears in industrial applications and as a precursor for vitamin E synthesis


The Formula

Solubility
Both
Optimal pH N/A
0 7 14

Stability

Crystalline solid with melting point 62-72°C; stable under proper storage but susceptible to oxidation in presence of specific catalysts

Conflicts

  • bases
  • acid anhydrides
  • acid chlorides
  • copper compounds
  • strong oxidizing agents

Safety

CIR Status
Not reviewed
Sensitization risk High

Industrial safety data classifies pure substance as corrosive (H314) causing severe skin burns and potential sensitizer (H317). Despite GRAS status for food flavoring, topical cosmetic safety remains unassessed by regulatory bodies.



Our Assessment

Avoid

High sensitization risk and corrosive potential make this ingredient unsuitable for topical skincare applications despite antioxidant properties.


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