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1-NITROPROPANE.

Avoid CAS 108-03-2 / SOLVENT

An industrial solvent compound occasionally found in cosmetic formulations as a processing agent or solvent, particularly in nail care products. This nitroalkane derivative serves no beneficial skincare function and is primarily recognized for its solvent properties rather than any therapeutic application. Its presence in skincare formulations is considered incidental rather than intentional for skin benefits.

solvent processing agent

Science

Functions solely as a solvent or thinning agent without any biological activity on skin tissue. No documented mechanism exists for skin health improvement, as this compound lacks bioactive properties relevant to dermatological applications.


Research

Low confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

Not commonly used as an active ingredient for dusting purposes due to its industrial nature and lack of skincare benefits


The Formula

Solubility
Both
Optimal pH 6 – 6
0 7 14

Stability

Maintains stability under standard storage conditions with aqueous solutions achieving pH 6.0. Exhibits high flammability with flash point between 34-36°C. Limited water solubility at 1.4-1.5% while showing complete miscibility with ethanol and ethyl ether.

Conflicts

  • Strong oxidizing agents
  • Strong bases/alkalis
  • Amines
  • Metal oxides
  • Strong acids
  • Some forms of plastics and rubber

Safety

CIR Status
Not reviewed
Pregnancy
Caution
Sensitization risk High

Classified as toxic via inhalation and ingestion with documented skin and eye irritation potential. Not evaluated by CIR for cosmetic safety assessment. Regulatory agencies identify its use primarily in nail brush cleaners rather than leave-on skincare applications.



Our Assessment

Avoid

An industrial solvent with no skincare benefits and significant safety concerns that should be avoided in precision skincare formulations.


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