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Moumoujus

1-METHYL-4-METHYLVINYL-CYCLOHEXANOL.

Questionable CAS 138-87-4 / PERFUMING

A naturally-occurring tertiary alcohol compound that delivers dual antimicrobial and sensory benefits to skincare formulations. This terpene-based ingredient activates cooling receptors on skin while demonstrating targeted activity against acne-causing bacteria when used in synergistic combinations.

Summary

antimicrobial cooling agent fragrance

Science

Mechanism of Action

Modulates TRPM8 cooling receptors to provide immediate sensory relief while disrupting bacterial cellular functions. Shows enhanced antimicrobial efficacy through synergistic interactions, particularly with thymol, targeting Cutibacterium acnes and Staphylococcus species without compromising beneficial skin microbiome balance.

Research

Clinical Evidence

Medium confidence
Effective range 0.01–5%
Optimal

0.1%

Key findings

  1. 01 Synergistic antimicrobial effects with thymol against acne-related bacteria while preserving microbiome balance
  2. 02 Tyrosinase inhibition and anti-melanogenesis activity in melanoma cell models

Transparency

Dusting Analysis

Not commonly dusted

Primarily used as fragrance component at very low concentrations (<0.01%) rather than as active ingredient

The Formula

Formulation

Solubility
Oil
Optimal pH 3.5 – 10
0 7 14

Stability

Resistant to oxidation under mild conditions but susceptible to acid-catalyzed dehydration reactions

Synergies

  • thymol

Conflicts

  • strong oxidizing agents
  • strong acids
  • strong bases

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk High

Classified as Category 1 skin sensitizer and Category 2 irritant; typically used at fragrance levels below 0.01%

Our Assessment

Verdict

Questionable

High sensitization risk limits practical application despite promising antimicrobial properties.

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References

Sources