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Moumoujus

1,4-BUTANEDIOL DIMETHACRYLATE.

Avoid CAS 2082-81-7 / FILM FORMING

This difunctional crosslinking monomer primarily serves to strengthen polymer networks in industrial applications, enabling the creation of robust, UV-curable systems. Despite its capacity for film formation, its classification as a strong skin sensitizer and irritant makes it unequivocally unsuitable for direct use in skincare formulations.

Summary

film-forming agent

Science

Mechanism of Action

1,4-Butanediol Dimethacrylate (BDDMA) operates as a difunctional crosslinking monomer, efficiently copolymerizing with other monomers to establish highly interconnected polymer networks. This process enhances material attributes such as hardness, chemical resistance, and dimensional stability. Its chemical properties also allow it to function as a film-forming agent, though this is primarily relevant in its industrial context.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 An in vitro investigation utilizing HL-60 cells indicated that 1,4-butanediol dimethacrylate can induce cell differentiation at toxic concentrations, with observed cytotoxicity potentially stemming from mitochondrial dysfunction affecting glucose metabolism. This research was specifically focused on biocompatibility for dental materials and did not assess skincare efficacy.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

1,4-Butanediol Dimethacrylate is highly susceptible to polymerization, a reaction that can be initiated by exposure to light, free radical initiators, iron, rust, and strong bases. To maintain stability during storage and handling, it is critical to monitor the levels of stabilizing inhibitors, such as hydroquinone (typically maintained at 75 ppm), and dissolved oxygen. For viscous material, heating up to a maximum of 60°C for periods not exceeding 24 hours may be necessary to facilitate transfer.

Conflicts

  • light exposure
  • free radical initiators
  • iron
  • rust
  • strong bases

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk High

1,4-Butanediol Dimethacrylate is designated as a hazardous substance under OSHA 29 CFR 1910.1200. It is classified by REACH/CLP as a Skin Sensitization Category 1B, indicating a significant potential to cause allergic skin reactions. Furthermore, it is categorized as a Skin Irritant Category 2 and an Eye Irritant Category 2. While the US EPA has revised its stance, no longer classifying acrylates and methacrylates as de facto carcinogens, its use remains primarily industrial, with no direct consumer cosmetic applications identified.

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
No Sensitive
Irritancy High
Comedogenicity Unknown

Our Assessment

Verdict

Avoid

This ingredient is classified as a potent skin sensitizer and irritant, lacks any identified cosmetic benefits, and is solely utilized in industrial applications, rendering it entirely inappropriate for any skincare formulation.

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