Science
Mechanism of Action
1,3-Dimethyl-3-phenylbutyl acetate functions by delivering a distinct aromatic profile, specifically an herbal-fruity scent reminiscent of fresh grapefruit, to a formulation.
Research
Clinical Evidence
Insufficient-data confidenceN/A
Transparency
Dusting Analysis
As a pure fragrance ingredient, 1,3-dimethyl-3-phenylbutyl acetate does not offer direct therapeutic or functional benefits for skin health. Its inclusion in precision skincare primarily serves an aesthetic purpose, thus its necessity should be evaluated based on a brand's specific philosophy regarding fragrance.
The Formula
Formulation
Stability
This ingredient exhibits oil solubility and is soluble in alcohol, with very low water solubility reported at 6.587 mg/L at 25°C. Like other acetates, it may gradually form acetic acid over time. It demonstrates good to very good stability in various product matrices including body lotions, shampoos, soaps, and deodorants, but shows poor stability when formulated with bleach.
Conflicts
- bleach
Safety
Safety Profile
The Research Institute for Fragrance Materials (RIFM) has conducted a safety assessment and determined that 1,3-dimethyl-3-phenylbutyl acetate is not considered a skin sensitizer. It tested positive for cytotoxicity without metabolic activation in a BlueScreen assay but was negative with metabolic activation, and also negative for genotoxicity both with and without metabolic activation. The recommended maximum usage level in fragrance concentrates is 5.0%.
Your Skin
Skin Compatibility
Our Assessment
Verdict
1,3-Dimethyl-3-phenylbutyl acetate serves solely as a fragrance component, offering an herbal-fruity aroma, and has been assessed by RIFM to have a low sensitization risk, though its specific irritancy and comedogenicity for skin are currently unknown.
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