Science
Mechanism of Action
It regulates sebum by inhibiting 5-α reductase and offers antibacterial action against P. acnes and S. albus. Additionally, it acts as a humectant, supports skin barrier function, and provides anti-inflammatory and antioxidant benefits.
Research
Clinical Evidence
High confidence1%
Key findings
- 01 1% concentration significantly decreased sebum levels after 4 weeks.
- 02 0.75% concentration completely inhibited Propionibacterium acnes growth.
- 03 0.25% concentration completely inhibited Staphylococcus albus growth.
- 04 Topical applications significantly reduced acne lesions by 40% over 8 weeks.
- 05 Skin treated with Zinc PCA showed a 30% increase in hydration levels over four weeks.
Transparency
Dusting Analysis
No specific data suggests Zinc PCA is commonly dusted in formulations.
The Formula
Formulation
Stability
Stable at room temperature; avoid temperatures above 60°C. Maintaining pH 5.0-7.0 is crucial for solubility and sustained bioavailability, with risk of precipitation outside pH 4.0-8.0.
Conflicts
- Alkaline components (e.g., NaOH)
Safety
Safety Profile
The CIR Expert Panel found Zinc PCA and other zinc salts safe when non-irritating. EU regulation limits it to 1% zinc (4.9% Zinc PCA). Topical use is low risk during pregnancy, but professional consultation is advised.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Zinc PCA is a highly effective, well-tolerated multi-functional ingredient for balancing skin, reducing acne, and providing hydration across all skin types.
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