Science
Mechanism of Action
This ingredient releases zinc ions to inhibit microbial growth and reduce inflammation by modulating cytokine production. It also strengthens the skin barrier, minimizes transepidermal water loss, and controls sebum by interfering with 5α-reductase and lipid synthesis.
Research
Clinical Evidence
High confidence2.5%
Key findings
- 01 Dermatology Research and Practice (2020)
- 02 Study by [7] (clinical studies on sebum regulation)
- 03 Experimental Dermatology (2019)
- 04 Journal of Applied Microbiology (2018)
- 05 Pharmaceutics (2021)
Transparency
Dusting Analysis
No data available in the provided research for dusting analysis.
The Formula
Formulation
Stability
Zinc Neodecanoate is stable under normal storage conditions. It is insoluble in water but dispersible in aqueous systems with appropriate surfactants or emulsifiers.
Conflicts
- Oxidizing agents
Safety
Safety Profile
The CIR panel deemed it safe for use up to 5% in leave-on and 10% in rinse-off formulations, with poor systemic absorption. However, EWG expresses concerns about its persistence, bioaccumulation, and potential toxicity in animal studies.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Zinc Neodecanoate is a valuable multi-functional ingredient, clinically proven to address acne, regulate sebum, and enhance skin barrier function, with a good safety profile for leave-on products up to 5%.
Related
Similar Ingredients
Finding similar ingredients…
References
Sources