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ZINC NEODECANOATE.

Valuable CAS 27253-29-8 / ANTICAKING, OPACIFYING, VISCOSITY CONTROLLING

Zinc Neodecanoate is a multi-functional ingredient that effectively targets acne, regulates sebum, and enhances skin hydration. It also provides antimicrobial and anti-inflammatory benefits for comprehensive skin health.

Antimicrobial Anti-inflammatory Sebum regulation Barrier strengthening Hydration boosting Deodorizing Anticaking Opacifying Viscosity controlling

Science

This ingredient releases zinc ions to inhibit microbial growth and reduce inflammation by modulating cytokine production. It also strengthens the skin barrier, minimizes transepidermal water loss, and controls sebum by interfering with 5α-reductase and lipid synthesis.


Research

High confidence
Effective range 1–5%
Optimal

2.5%

Key findings

  1. 01 Dermatology Research and Practice (2020)
  2. 02 Study by [7] (clinical studies on sebum regulation)
  3. 03 Experimental Dermatology (2019)
  4. 04 Journal of Applied Microbiology (2018)
  5. 05 Pharmaceutics (2021)

Transparency

Not commonly dusted

No data available in the provided research for dusting analysis.


The Formula

Solubility
Oil
Optimal pH 5.5 – 7.5
0 7 14

Stability

Zinc Neodecanoate is stable under normal storage conditions. It is insoluble in water but dispersible in aqueous systems with appropriate surfactants or emulsifiers.

Conflicts

  • Oxidizing agents

Safety

CIR Status
Safe with restrictions
Max tested
5%
Sensitization risk Low

The CIR panel deemed it safe for use up to 5% in leave-on and 10% in rinse-off formulations, with poor systemic absorption. However, EWG expresses concerns about its persistence, bioaccumulation, and potential toxicity in animal studies.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

Zinc Neodecanoate is a valuable multi-functional ingredient, clinically proven to address acne, regulate sebum, and enhance skin barrier function, with a good safety profile for leave-on products up to 5%.


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