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ZINC ACETATE.

Valuable CAS 557-34-6 / ANTIMICROBIAL

Zinc acetate is a versatile ingredient known for its antimicrobial and astringent properties, effectively addressing various dermatological concerns including acne and inflammatory conditions. It helps protect and tighten the skin while supporting overall skin health.

Antimicrobial Astringent Anti-inflammatory Skin Protectant Antioxidant

Science

It reduces microbial colonization, acts as an astringent, and protects compromised skin. Its anti-inflammatory effects are mediated by regulating immune cell functions and modulating inflammatory cytokines, while also providing antioxidant benefits.


Research

High confidence
Effective range 1–1.2%
Optimal

1%

Key findings

  1. 01 Effective at 1% for dermatological conditions like acne, dermatitis, psoriasis, eczema, and rosacea by reducing inflammation and promoting skin healing.
  2. 02 Evaluated at 1.2% for pruritus and erythema in seborrheic dermatitis.
  3. 03 Products with zinc acetate (with or without erythromycin) were found to be equal or superior to other standalone acne treatments.

Transparency

Not commonly dusted

No specific information regarding dusting behavior was found in the provided research data.


The Formula

Solubility
Water
Optimal pH 5 – 8
0 7 14

Stability

A 1% solution has a pH of approximately 7, while a 5% solution ranges from pH 6.0 to 8.0. The anhydrous form is hygroscopic and readily converts to the dihydrate upon air exposure.

Synergies

  • Erythromycin

Conflicts

  • Other zinc salts
  • Alkalies and their carbonates
  • Oxalates
  • Phosphates
  • Strong bases

Safety

CIR Status
Safe as used
Max tested
1%
Sensitization risk Low

The CIR Panel concluded zinc acetate is safe in cosmetics at current uses and concentrations when formulated to be non-irritating. Topical 1% solutions are generally safe, but a patch test is recommended, and it should not be applied to open wounds or irritated skin.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Valuable

Zinc Acetate is a valuable multi-functional ingredient, offering antimicrobial, astringent, and anti-inflammatory benefits for various skin conditions within established safe concentrations.


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