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ZEIN.

Insufficient Data CAS 9010-66-6 / FILM FORMING, HAIR CONDITIONING, SKIN CONDITIONING

Zein is a plant-based protein known for its film-forming properties, creating a protective layer on the skin. This layer helps to lock in moisture, protect against environmental pollutants, and provide a smooth, even surface.

Film-forming Hair conditioning Skin conditioning

Science

It forms a thin film, retaining water through hydrogen bonds and resisting water/grease penetration. Zein-based films have been studied for roles in wound healing, inhibiting matrix metalloproteinases, and promoting glycosaminoglycan and collagen biosynthesis to combat skin aging.


Research

Low confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

No specific data was found regarding Zein being commonly dusted in cosmetic formulations.


The Formula

Solubility
Unknown
Optimal pH 2 – 9
0 7 14

Stability

Zein is soluble in alcohol solutions (e.g., ethanol) and alcohol-water mixtures but insoluble in water. Zein nanoparticles show improved stability across a pH range of 2 to 9.


Safety

CIR Status
Not reviewed
Sensitization risk Low

The CIR has not reviewed Zein for cosmetic use. It is 'Generally Recognized As Safe' (GRAS) by the FDA for food-related applications, and EWG notes 'LOW' concerns for allergies and immunotoxicity.


Your Skin

Yes Normal
Yes Dry
No Oily
Yes Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Insufficient Data

Zein offers beneficial film-forming and skin conditioning properties; however, there is insufficient specific clinical efficacy data for its use in skincare and no dedicated CIR review.


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