Science
Mechanism of Action
It functions as an antioxidant and anti-inflammatory agent, demonstrated by COX-1 inhibition. Additionally, it exhibits antimicrobial effects against various pathogens and aids in wound healing.
Research
Clinical Evidence
Medium confidenceN/A
Key findings
- 01 Demonstrated concentration-dependent antimicrobial activity against various oral pathogens.
- 02 Showed over 90% in vitro inhibitory activity of COX-1, indicating anti-inflammatory potential.
Transparency
Dusting Analysis
No specific data available suggests this ingredient is commonly used at sub-efficacious 'dusting' levels in cosmetic formulations.
The Formula
Formulation
Stability
No specific stability notes or optimal pH range have been identified for cosmetic formulation.
Safety
Safety Profile
The CIR has not reviewed this ingredient, and dermal toxicity for the branch/leaf extract is not determined. While the plant's general toxicological profile is benign, high concentrations of root bark extracts showed in vitro cytotoxic effects.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Despite promising antioxidant, anti-inflammatory, and antimicrobial in vitro findings, more comprehensive data is required to establish its full safety and efficacy in topical cosmetic applications.
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