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YTTRIUM OXIDE.

Questionable CAS 1314-36-9 / NOT REPORTED

Yttrium Oxide (Y2O3) is a rare earth compound with potential multifaceted benefits for skin, including antibacterial, antioxidant, and tissue regenerative properties. It also shows selective cytotoxic activity against certain cancer cells.

Antibacterial Antioxidant Tissue regeneration Angiogenesis Anti-aging (potential) UV protection (potential)

Science

As nanoparticles, Yttrium Oxide acts as an antibacterial by disrupting bacterial metabolism and as an antioxidant by neutralizing reactive oxygen species. It also promotes tissue repair and angiogenesis by upregulating key growth factors.


Research

Medium confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 Yttrium Oxide Nanoparticle Synthesis: An Overview of Methods of Preparation and Biomedical Applications.
  2. 02 Yttrium oxide nanoparticle loaded scaffolds with enhanced cell adhesion and vascularization for tissue engineering applications.
  3. 03 Y2O3NPs induce selective cytotoxicity, genomic instability, oxidative stress and ROS mediated mitochondrial apoptosis in human epidermoid skin A-431 Cancer cells.

Transparency

Not commonly dusted

Yttrium Oxide is a specialized compound with defined mechanisms of action, not a common cosmetic filler ingredient typically used for 'dusting' at low, ineffective percentages.


The Formula

Solubility
Acid soluble
Optimal pH N/A
0 7 14

Stability

Yttrium Oxide is an air-stable, thermodynamically and thermally stable white solid, maintaining good chemical stability under normal conditions. Its stability can be enhanced by forming a complex with ZnO3.

Conflicts

  • strong acids
  • bases
  • oxidizing agents

Safety

CIR Status
Not reviewed
Sensitization risk High

Safety data sheets indicate Yttrium Oxide causes skin and serious eye irritation. No dedicated CIR, SCCS, or FDA cosmetic safety review exists, and long-term occupational exposure may have cumulative health effects.


Your Skin

No Normal
No Dry
No Oily
No Sensitive
Irritancy High
Comedogenicity Unknown

Our Assessment

Questionable

Despite promising in-vitro activities in antibacterial, antioxidant, and tissue regeneration, Yttrium Oxide lacks comprehensive safety reviews for cosmetic use and carries a high irritation risk.


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