Science
Mechanism of Action
This extract neutralizes free radicals, reduces inflammatory mediators like Nitric Oxide, and inhibits enzymes such as elastase and tyrosinase, leading to oxidative stress protection, reduced inflammation, improved elasticity, and inhibited melanin synthesis.
Research
Clinical Evidence
Medium confidenceN/A
Key findings
- 01 Up to 35.25% in vitro inhibition of Nitric Oxide production demonstrated anti-inflammatory capacity.
- 02 In vitro studies showed ~54% inhibition of anti-tyrosinase and ~98% inhibition of anti-elastase activity for anti-aging effects.
- 03 16–18 g/L (MIC, in vitro) inhibited the growth of common bacteria like S. aureus and E. coli.
Transparency
Dusting Analysis
There is no information to suggest that Vitis Labrusca Stem Extract is commonly used at ineffective 'dusting' levels in cosmetic formulations.
The Formula
Formulation
Stability
Phenolic compounds are water and alcohol-soluble. While an optimal pH range isn't defined, the extract is generally stable in formulations.
Safety
Safety Profile
While Vitis labrusca itself is not CIR reviewed, analogous Vitis vinifera extracts are deemed safe. In vivo animal studies showed no nephrotoxicity or hepatotoxicity, but formulators should ensure minimal pesticide and heavy metal residues.
Your Skin
Skin Compatibility
Our Assessment
Verdict
This ingredient offers broad-spectrum benefits, including potent antioxidant, anti-inflammatory, and anti-aging effects, making it a valuable addition to various skincare formulations.
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References
Sources