Science
Mechanism of Action
This extract combats free radicals and inhibits xanthan oxidase, demonstrating significant antioxidant activity in vitro. Its verbenalin content contributes to anti-inflammatory effects, while its astringent nature helps minimize pores and control sebum.
Research
Clinical Evidence
Medium confidenceN/A
Key findings
- 01 In vitro studies using 50% ethanolic extract showed high antiradical activity (IC50 21.04±1.61 µg/mL) and inhibited xanthan oxidase (IC50 12.77±1.65 µg/mL).
- 02 An aqueous extract also demonstrated high antiradical activity (IC50 33.8±0.43 µg/mL) and inhibited xanthan oxidase (IC50 18.05±3.80 µg/mL) in vitro.
Transparency
Dusting Analysis
The Formula
Formulation
Stability
The extract maintains stability within a pH range of 4.5-6.5 and can be prepared using water, ethanol, or hydro-alcoholic mixtures like 1,3-butylene glycol aqueous solution for optimal aglycone recovery.
Safety
Safety Profile
While CIR and SCCS safety assessments are not available, the European Pharmacopoeia includes Verbena officinalis, requiring a minimum 1.5% verbenaline, suggesting recognized quality for medicinal use.
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