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Moumoujus

VANILLYL BUTYL ETHER.

Valuable CAS 82654-98-6 / FRAGRANCE, HAIR CONDITIONING, ORAL CARE, SKIN CONDITIONING

Vanillyl Butyl Ether (VBE) is a sensory agent that delivers a gentle, lasting warming sensation to the skin. This effect enhances blood microcirculation and can improve the absorption of other active ingredients.

Summary

Warming agent Fragrance ingredient Hair conditioning Masking Oral care agent Skin conditioning

Science

Mechanism of Action

VBE primarily functions by activating the Transient Receptor Potential Vanilloid 1 (TRPV1) receptor on the skin, inducing warmth. This activation increases blood microcirculation and triggers the release of neurotransmitters, contributing to increased localized skin temperature.

Research

Clinical Evidence

High confidence
Effective range 0.1–1%
Optimal

0.2%

Key findings

  1. 01 Clinical studies show VBE is generally well-tolerated at 0.1%-1%, though higher concentrations may induce temporary redness or tingling. It has been investigated for its ability to topically induce blood cell flux and warming sensations.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Oil
Optimal pH 3 – 10
0 7 14

Stability

VBE is stable across a wide pH range (3-10) but can degrade with exposure to extreme temperatures, light, air, or strong oxidants. It is best incorporated into formulations below 60°C, ideally under 40°C, and is more stable in emulsions.

Synergies

  • emollients
  • esters
  • oils

Conflicts

  • strong oxidants
  • extreme temperatures
  • light
  • air

Safety

Safety Profile

CIR Status
Safe as used with restrictions
Max tested
1%
Sensitization risk Moderate

The CIR Expert Panel deems VBE safe up to 1% if non-irritating, with an EWG score of 1. However, it can cause serious eye irritation and is classified as a skin sensitizer, necessitating proper patch testing prior to widespread use.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Valuable

Vanillyl Butyl Ether is a valuable warming agent that enhances microcirculation and active ingredient absorption, suitable for a range of formulations within specified concentrations.

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