Science
Mechanism of Action
Its action includes membrane damage for antifungal effects and contains bioactive compounds like cardiac glycosides, saponins, and flavonoids, with phenolic compounds contributing to its significant antioxidant activity.
Research
Clinical Evidence
Medium confidence2%
Key findings
- 01 A 2% lotion significantly supported hair regrowth in 45% of patients with patchy alopecia areata.
- 02 Demonstrated antifungal efficacy against P. digitatum (EC50: 69.01 ± 2.29 µg/well) and C. graminicola (EC50: 86.89 ± 1.17 μg/well).
- 03 Exhibited high antibacterial activity against S. aureus (66.81 ± 1.06%) and B. subtilis (57.94 ± 0.92%).
- 04 Showed strong antioxidant activity, with ethanol extracts demonstrating 72.67% and methanol extracts 66.89% free radical scavenging.
Transparency
Dusting Analysis
The Formula
Formulation
Conflicts
- Potential interactions with medicines having similar (e.g., digoxin) or opposing effects if systemic absorption occurs.
Safety
Safety Profile
This extract contains toxic cardiac glycosides and scilliroside, presenting a high risk of toxicity with systemic absorption and making it a gastric irritant. It is contraindicated for individuals with cardiac disorders and lacks official cosmetic safety evaluation.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Despite promising in vitro and limited clinical efficacy, the inherent severe toxicity, documented cardiotoxic compounds, and lack of cosmetic safety evaluations render Urginea Maritima Tuber Extract unsafe for precision skincare.
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References
Sources