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UREA-D-GLUCURONIC ACID.

Insufficient Data / HAIR CONDITIONING, HUMECTANT

UREA-D-GLUCURONIC ACID combines urea's powerful humectant and keratolytic actions with D-glucuronic acid's moisturizing, exfoliating, and structural support properties for skin and hair.

Humectant Hair Conditioning Keratolytic Skin Barrier Support Antimicrobial Peptide Expression Cell Turnover Promotion Skin Firmness & Structure Support pH Regulation Chelating

Science

This compound enhances moisture retention and gently exfoliates by breaking down keratin. It also supports skin barrier function, promotes cell turnover, and aids in the biosynthesis of glycosaminoglycans for improved firmness.


Research

Low confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

The Formula

Solubility
Water
Optimal pH N/A
0 7 14

Stability

Urea is most stable at pH 4-8, with optimal stability at pH 6.0; cyanate accumulation can be prevented at pH 4.7 or 5°C. D-Glucuronic Acid is generally stable and weakly acidic (pKa 3.21).


Safety

CIR Status
Not reviewed
Pregnancy
Caution
Sensitization risk Moderate

While rated low concern by EWG Food Scores (1), specific CIR, SCCS, or FDA status for the combined ingredient is unavailable. D-Glucuronic Acid can be an irritant (GHS classification 50% of the time), and Urea may cause stinging at higher concentrations. Avoid use during pregnancy or breastfeeding due to insufficient data.


Your Skin

No Normal
No Dry
No Oily
No Sensitive
Irritancy Moderate
Comedogenicity Unknown

Our Assessment

Insufficient Data

This ingredient shows potential for hydration, exfoliation, and structural benefits, but further specific safety and efficacy data for the combined molecule is required for a definitive rating.


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