Science
Mechanism of Action
This ingredient disrupts fungal cell membranes, increasing permeability and leading to cellular dysfunction and death. It also inhibits fungal morphogenesis, preventing invasive hyphal forms and biofilm formation of Candida albicans.
Research
Clinical Evidence
High confidence10%
Key findings
- 01 A 25% concentration visibly improved nail health for 68% of onychomycosis patients after 12 weeks of consistent application.
- 02 Concentrations above 3 mM effectively inhibit Candida albicans biofilm formation, with >4 mM abolishing its yeast-to-filamentous phase transition.
Transparency
Dusting Analysis
The Formula
Formulation
Stability
Antifungal activity is effective within the pH range of 4.5 to 6.0, with better efficacy observed at lower pH values within this range. Specific chemical stability pH for the ingredient itself is not detailed.
Conflicts
- Avoid use on pus-containing sores or badly broken skin.
- Keep away from eyes, nose, mouth, and vagina.
- Flammable in spray form; avoid heat/open flame.
Safety
Safety Profile
The CIR Expert Panel deemed it safe up to 25% when formulated to be non-irritating. It is FDA-approved for topical OTC antifungal use (10-25% total undecylenate) and used as a preservative in EU cosmetics.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Undecylenic acid is a valuable, FDA-approved antifungal agent for targeted treatments of superficial fungal and yeast infections, also offering beneficial preservative properties in skincare formulations.
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