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Moumoujus

TURNERA DIFFUSA LEAF EXTRACT.

Insufficient Data CAS 84696-52-6 / SKIN CONDITIONING

Turnera Diffusa Leaf Extract, derived from the Damiana plant, is a botanical ingredient recognized for its promising antiphotoaging capabilities. It actively defends skin cells against UVB-induced oxidative stress and supports collagen integrity for a more resilient complexion.

Summary

Skin-Conditioning Agent Antioxidant Anti-aging agent Collagen booster ROS scavenger

Science

Mechanism of Action

This extract operates by mitigating the damaging effects of UVB radiation. It effectively blocks the overproduction of reactive oxygen species (ROS) in skin cells and reduces the expression of matrix metalloproteinases (MMPs), enzymes responsible for collagen degradation. Simultaneously, it stimulates procollagen type I synthesis and upregulates the Nrf2/ARE signaling pathway, a crucial defense mechanism against oxidative stress. Its action also involves decreasing the phosphorylation of c-Jun and c-Fos, key components of the AP-1 pathway, and inhibiting Smad-7 expression within the TGF-β/Smad pathway, collectively leading to enhanced collagen production and protection.

Research

Clinical Evidence

Medium confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

No data available in the provided research regarding 'dusting' properties or thresholds for Turnera Diffusa Leaf Extract.

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Safety

Safety Profile

CIR Status
Insufficient data
Pregnancy
Caution
Sensitization risk Unknown

Formal cosmetic safety assessments by CIR or SCCS are not available, and general safety data for cosmetic applications are limited. The ingredient contains potentially concerning chemicals such as arbutin, tannins, and cyanogenic glycosides. Due to the presence of potential cyanogenic glycosides and a lack of adequate research, use during pregnancy or lactation should be avoided. While Turnera diffusa has a status of 'generally safe for medicinal use' by the FDA, its safety and effectiveness specifically as a cosmetic ingredient have not been reviewed by the FDA. Comprehensive clinical trial data, including dosage recommendations for cosmetic use, are currently lacking.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Insufficient Data

While Turnera Diffusa Leaf Extract shows promising antiphotoaging and antioxidant effects in preliminary studies, the lack of comprehensive safety data and formal cosmetic assessments warrants a cautious approach, categorizing it as an ingredient with insufficient data for definitive recommendation.

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