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Moumoujus

TRITICUM AESTIVUM PEPTIDE.

Insufficient Data CAS 100684-25-1 / FILM FORMING, HAIR CONDITIONING, SKIN CONDITIONING

Triticum Aestivum Peptide, derived from wheat, functions as a multi-faceted skin and hair conditioning agent, and a film former. It actively supports skin health by contributing to anti-inflammatory responses and enhancing the skin's natural reparative processes through cellular regeneration and collagen promotion.

Summary

film forming hair conditioning skin conditioning anti-inflammatory wound healing collagen boosting elasticity enhancing

Science

Mechanism of Action

Triticum Aestivum Peptide operates through several key mechanisms to benefit the skin. Specific wheat germ-derived peptides, such as YDWPGGRN, exhibit anti-inflammatory activity by significantly suppressing the production of pro-inflammatory markers (NO, IL-1β, IL-6, TNF-α) while simultaneously boosting the release of the anti-inflammatory cytokine IL-10. This peptide also enhances the proliferation and migration of both keratinocytes (HaCaT cells) and fibroblasts (L929 cells), which are essential for skin repair. Furthermore, it stimulates angiogenesis (blood vessel formation) and collagen production, thereby accelerating wound-healing. Aqueous extracts of Triticum aestivum have been shown to accelerate tissue repair by modulating crucial remodeling biomarkers, including MMP-2 and MMP-9, and strengthening matrix structure components like collagen I, elastin, integrin αV, and aquaporin 3, ultimately improving dermal tissue remodeling and elasticity.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Stability

Specific optimal pH range for stability for Triticum Aestivum Peptide in cosmetic formulations is not available.

Safety

Safety Profile

CIR Status
Insufficient data
Sensitization risk Moderate

The Cosmetic Ingredient Review (CIR) Expert Panel concluded that the available data are insufficient to make a determination of safety for Triticum Aestivum Peptide in cosmetics. General wheat-derived ingredients have been associated with work-related sensitization, particularly in bakery workers, and wheat allergies affect populations globally. Respiratory IgE-mediated allergies to wheat proteins (e.g., baker's asthma) are recognized occupational diseases, and bronchial reactivity to inhaled wheat proteins in adults with food allergy, though rare, has been documented. Industry is advised to utilize good manufacturing practices to limit impurities in botanical ingredients.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Insufficient Data

While mechanistic studies suggest promising benefits for skin repair, anti-inflammation, and elasticity, the CIR's classification of 'insufficient data' for safety, alongside known wheat allergy concerns, warrants careful consideration and further research for widespread cosmetic application.

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