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Moumoujus

TRISILOXANE.

Valuable CAS 107-51-7 / ANTIFOAMING, SKIN CONDITIONING

Trisiloxane is a light, volatile silicone fluid recognized for its ability to enhance skin conditioning and improve product application. It imparts a soft, smooth, and non-greasy finish, while also facilitating moisture retention and boosting the efficacy of other ingredients.

Summary

Skin Conditioning Antifoaming Carrier

Science

Mechanism of Action

Trisiloxane functions primarily as a skin conditioning agent and anti-foaming ingredient. Its low viscosity allows for easy spreadability and quick evaporation, leaving behind a non-greasy, silky, dry-smooth finish without residue. On the skin, it forms a thin, vapor-permeable barrier that effectively reduces transepidermal water loss, thus supporting skin hydration. Furthermore, Trisiloxane acts as an excellent carrier, optimizing the distribution and penetration of other active compounds within a formulation.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

No data is available within the provided research to indicate that Trisiloxane commonly experiences 'dusting' or to establish specific dusting thresholds.

The Formula

Formulation

Solubility
Oil
Optimal pH 5 – 9
0 7 14

Stability

Trisiloxane exhibits hydrolytic instability at extreme pH levels; solutions at pH 4 became hazy within one day, and at pH 10 within three days. Optimal stability, extending beyond 2 years, is achieved by buffering solutions to a neutral pH. It maintains stability for approximately one month under weakly alkaline conditions (pH 8), but degrades significantly at pH 2 or 3 within ten days to a month.

Synergies

  • Enhances penetration and efficacy of other active ingredients by acting as an effective carrier.

Conflicts

  • Extremely acidic pH (e.g., pH 4 or lower)
  • Strongly alkaline pH (e.g., pH 10 or higher)

Safety

Safety Profile

CIR Status
Safe as used
Sensitization risk Low

The CIR (Cosmetic Ingredient Review) Expert Panel deemed Trisiloxane, including its synonym Hexyl Methicone, safe for use in cosmetics, citing its large molecular weight which limits significant skin absorption and its typical use in low concentrations. It is generally well-tolerated on skin and non-comedogenic. Health Canada classifies it as an acceptable non-medicinal ingredient in natural health products. The SCCS (Scientific Committee on Consumer Safety) issued a preliminary opinion stating it could not conclude on the safety of octamethyltrisiloxane (Trisiloxane), though the detailed SCCS opinions provided primarily pertain to Triclocarban and Triclosan, not Trisiloxane. The FDA does not typically pre-approve cosmetic ingredients; however, a related compound, Drometrizole Trisiloxane, is under review by the FDA as a potential sunscreen active ingredient, which is distinct from Trisiloxane as a cosmetic conditioning agent.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Valuable

Trisiloxane is a valuable cosmetic ingredient, enhancing product feel, spreading, and active ingredient delivery with a good safety and skin compatibility profile.

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