Science
Mechanism of Action
This ingredient functions as a derivative of Hexamethylene Diisocyanate (HDI) Isocyanurate Trimer. The core HDI Isocyanurate Trimer is known for forming polyurethane materials, suggesting its potential for film creation or molecular cross-linking. The 'Acryloyl' component further indicates its capacity to act as a crosslinking agent, capable of polymerization under specific conditions, such as UV exposure. Its documented activity is focused on enhancing the protective and adherence properties in nail products.
Research
Clinical Evidence
Low confidenceN/A
Transparency
Dusting Analysis
The Formula
Formulation
Stability
The foundational Hexamethylene Diisocyanate Isocyanurate Trimer is susceptible to degradation by air and heat, necessitating storage in an inert atmosphere and refrigeration. Isocyanate groups are inherently reactive with water and compounds containing active hydrogens, which are critical considerations during formulation.
Conflicts
- water
- compounds with active hydrogens
- general incompatible materials
Safety
Safety Profile
The Cosmetic Ingredient Review (CIR) Expert Panel has not evaluated TRIS-ACRYLOYL PPG-6 HDI ISOCYANURATE TRIMER. The base compound, Hexamethylene Diisocyanate Isocyanurate Trimer, is associated with a moderate risk of allergic skin reactions (H317), is harmful if inhaled (H332), and may cause respiratory irritation (H335), in addition to being a moderate skin and eye irritant. These classifications pertain to the industrial form of the trimer. A related derivative holds FDA Food Contact Substance (FCS) status for adhesives, subject to specific restrictions and barrier separation from food.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Primarily identified for nail conditioning with no established benefits for skin and notable safety concerns from its base compound, this ingredient is not recommended for precision skincare applications.
Related
Similar Ingredients
Finding similar ingredients…