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Moumoujus

TRIPEPTIDE-7 SH-DECAPEPTIDE-9.

Insufficient Data CAS - / SKIN PROTECTING

TRIPEPTIDE-7 SH-DECAPEPTIDE-9 is a synthetically engineered human peptide designed to precisely mimic the natural protein endorphin. Its SH-Decapeptide-7 component acts as a neuropeptide, mirroring Met-Enkephalin, to help modulate the skin's response to various environmental and internal stressors. This ingredient is implicated in both anti-aging applications and supporting the skin's natural wound healing processes.

Summary

Skin protecting Anti-aging Wound healing Muscle relaxation

Science

Mechanism of Action

This peptide operates by stimulating skin nerve cells to release met-enkephalin, a neurochemical known for its regulatory role in the body's response to harmful stimuli. This mechanism is believed to lead to muscle relaxation, potentially reducing the appearance of expression lines, and contributes to reduced inflammation. By interacting with neural pathways in the skin, it supports protective and reparative functions.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 Research on related peptides indicates potential benefits: Cyclized Hexapeptide-9, at a concentration of 0.002%, demonstrated a significant decrease in the number, area, and roughness of crow's feet and forehead wrinkles over 56 days.
  2. 02 Palmitoyl Tripeptide-1, applied at 4 ppm, resulted in a 39% decrease in wrinkle length, a 23% decrease in wrinkle depth, and a 17% decrease in overall skin roughness over a 4-week period.
  3. 03 A multi-component anti-aging topical eye cream containing Palmitoyl Tripeptide-1 and Palmitoyl Tetrapeptide-7 exhibited substantial enhancements in skin hydration (28.12%), elasticity (18.81%), and collagen production (54.99%) after 12 weeks.

Transparency

Dusting Analysis

Not commonly dusted

No information regarding common dusting practices, thresholds, or red flag percentages is available for this specific peptide combination.

The Formula

Formulation

Solubility
Unknown
Optimal pH N/A
0 7 14

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Low

Direct safety assessments by regulatory bodies such as CIR, SCCS, or FDA for TRIPEPTIDE-7 SH-DECAPEPTIDE-9 are currently unavailable. However, related peptides, including Tripeptide-1 and Palmitoyl Tetrapeptide-7, have been deemed safe for cosmetic use at low concentrations (e.g., below 10 ppm or 0.002%), showing negative data for repeated dosage toxicity, skin irritation, sensitization, and genotoxicity. This suggests a potentially favorable safety profile, though specific studies for this combination are needed.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Verdict

Insufficient Data

TRIPEPTIDE-7 SH-DECAPEPTIDE-9 offers a promising neuropeptide-mimicking mechanism for anti-aging and skin protection, yet direct clinical efficacy studies for this specific combination are currently limited, necessitating further research for a definitive evaluation.

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