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Moumoujus

TRIPEPTIDE-61.

Insufficient Data / SKIN CONDITIONING

TRIPEPTIDE-61 is a synthetic peptide composed of arginine, isoleucine, and phenylalanine, functioning primarily as a skin conditioning agent. It aims to diminish visible signs of aging by promoting collagen synthesis, thereby enhancing skin structure and resilience.

Summary

skin conditioning anti-aging collagen stimulation skin barrier support

Science

Mechanism of Action

This synthetic peptide operates by directly stimulating collagen production within the skin, which helps to fortify the skin's structural integrity. This action leads to a reduction in the appearance of wrinkles and fine lines, coupled with an improvement in overall skin resilience. Additionally, Tripeptide-61 contributes to enhanced skin tolerance against external factors and actively works to prevent epidermal dehydration. Its inherent properties include moderate self-assembly capabilities, good biocompatibility, amphoteric performance, and adjustable electrical characteristics, which allow it to stabilize nanocarriers in aqueous solutions.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

Clinical efficacy and precise usage concentration data for TRIPEPTIDE-61 are currently insufficient to establish a definitive dusting threshold.

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Stability

TRIPEPTIDE-61 demonstrates water solubility, and its peptide segment can effectively stabilize nanocarriers in aqueous formulations. General peptide stability is often enhanced by maintaining a pH between 3 and 5 to mitigate deamidation and oxidation, and to protect disulfide bridges. Optimal formulation considerations typically include precise pH control, strategic use of excipients and co-solvents, air exclusion, viscosity enhancement, and protection from light and fluctuating temperatures.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Unknown

TRIPEPTIDE-61 has not been specifically reviewed by major regulatory bodies such as CIR, SCCS, or FDA for safety. While assessments for other tripeptides (e.g., Tripeptide-1, Hexapeptide-12) generally indicate safety at low concentrations (typically below 10 ppm or 0.002%), with negative findings in toxicology, irritation, sensitization, and genotoxicity studies, these findings cannot be directly attributed to TRIPEPTIDE-61 due to its distinct molecular composition.

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
No Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Insufficient Data

TRIPEPTIDE-61 shows theoretical promise for collagen stimulation and anti-aging benefits, but lacks specific clinical studies and safety assessments to confirm its precise efficacy and safe use concentrations.

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