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Moumoujus

TRIMETHYLOLPROPANE TRIMETHACRYLATE.

Avoid CAS 3290-92-4 / FILM FORMING

Trimethylolpropane Trimethacrylate is an acrylate monomer known for its film-forming properties, primarily utilized in UV-curable systems to create durable polymer structures. While it can produce a continuous film on surfaces, its application to skin is associated with considerable irritation and sensitization risks.

Summary

film-forming

Science

Mechanism of Action

This ingredient functions as an acrylate monomer, serving as a foundational building block in UV-curable systems. Upon application, it undergoes polymerization to form a continuous, cohesive film on the skin, hair, or nails, which is its primary mechanism of action.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

No data available to suggest dusting behavior or associated risks for this ingredient in skincare applications.

The Formula

Formulation

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

Trimethylolpropane Trimethacrylate exhibits significant instability, prone to violent polymerization at temperatures exceeding 32°C, after 12 months of storage, or upon exposure to light, free radicals, or oxidizing agents. It is also hygroscopic and light-sensitive, necessitating stabilization (e.g., with MEHQ for related compounds) when exposed to heat and direct sunlight.

Conflicts

  • strong oxidizing agents
  • strong acids
  • strong bases
  • brass
  • copper
  • steel (all types and surface treatments)
  • iron and iron salts
  • light
  • heat
  • free radicals

Safety

Safety Profile

CIR Status
Safe with restrictions
Sensitization risk High

The CIR Expert Panel deems Trimethylolpropane Trimethacrylate safe only for use in nail enhancement products where direct skin contact can be effectively avoided, due to its significant sensitizing potential. The ingredient is classified by CIR as a 'Human skin toxicant or allergen' with strong evidence. It's crucial to differentiate this from Trimethylolpropane Triacrylate, a related compound, which is classified as possibly carcinogenic by IARC (Group 2B) and by California Proposition 65, classifications not directly attributed to Trimethylolpropane Trimethacrylate itself in the reviewed data.

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
No Sensitive
Irritancy High
Comedogenicity Unknown

Our Assessment

Verdict

Avoid

Due to a lack of documented skin benefits, high irritancy, strong sensitization potential, and CIR restrictions advising against skin contact, this ingredient is not suitable for precision skincare formulations targeting direct skin application.

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