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TRIMETHYL-PENTYL-DIOXANE.

Questionable CAS 63449-89-8 / PERFUMING

TRIMETHYL-PENTYL-DIOXANE encompasses a class of 1,3-dioxane derivatives, primarily incorporated into cosmetic formulations for its aromatic properties. Its principal function is to impart scent, rather than offering direct biological benefits for skin enhancement.

perfuming

Science

This ingredient operates by releasing volatile compounds that contribute to the fragrance profile of a product. It does not engage in known biological pathways to improve skin condition or address specific dermal concerns.


Research

Low confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

The Formula

Solubility
Oil
Optimal pH 5 – 10
0 7 14

Stability

1,3-Dioxane derivatives generally maintain stability across neutral to basic pH ranges, and under reductive or oxidative conditions. However, they are prone to degradation in acidic environments, particularly when exposed to strong Brönsted or Lewis acids.

Conflicts

  • Strong acids (Brönsted or Lewis acids)

Safety

CIR Status
Not reviewed
Sensitization risk Moderate

The Cosmetic Ingredient Review (CIR) Expert Panel has not specifically assessed TRIMETHYL-PENTYL-DIOXANE or its common isomers. It is important to distinguish this ingredient from 1,4-Dioxane, which is a manufacturing contaminant. For one specific isomer, 1,3-Dioxane, 4,4,6-trimethyl-2-pentyl- (CAS 63449-89-8), the European Chemicals Agency (ECHA) has issued a classification as a 'Skin Sensitizer Category 1', indicating its potential to cause an allergic skin reaction.


Your Skin

No Normal
No Dry
No Oily
No Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Questionable

As a fragrance component with no direct skin benefits and a moderate sensitization risk identified for a specific isomer, TRIMETHYL-PENTYL-DIOXANE is a questionable inclusion for precision skincare formulations.


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