Science
Mechanism of Action
As an occlusive glyceryl triester, Triisopalmitin forms a lubricating film on the skin's surface. This barrier helps to reduce transepidermal water loss, thus maintaining skin hydration and imparting a smooth, pliable feel. Furthermore, it has been observed to increase the percutaneous penetration of other chemical compounds within a product.
Research
Clinical Evidence
Low confidenceN/A
Transparency
Dusting Analysis
Triisopalmitin is typically incorporated as a functional ingredient for its emollient and viscosity-controlling properties, not merely for marketing claims at sub-efficacious concentrations.
The Formula
Formulation
Conflicts
- Due to its ability to increase the skin penetration of other chemicals, formulators should carefully consider ingredient combinations when incorporating Triisopalmitin to avoid unintended effects from other active compounds.
Safety
Safety Profile
The Cosmetic Ingredient Review (CIR) Expert Panel has concluded that Triisopalmitin, along with 50 other triglycerides and 22 additional glyceryl triesters, is safe for use in cosmetics. These ingredients are found in products at concentrations ranging from approximately 0.1% to 46%. It is important to note that the FDA does not pre-approve cosmetic ingredients; manufacturers are responsible for ensuring product safety.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Triisopalmitin is a valuable emollient and skin conditioner, safely utilized across a broad spectrum of formulations, though its demonstrated ability to enhance skin penetration warrants careful consideration during product development.
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References
Sources