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TRIETHYLAMINE.

Avoid CAS 121-44-8 / EMULSION STABILISING

Triethylamine is an organic base primarily utilized in cosmetic formulations for its ability to regulate pH and stabilize emulsions. However, its severe toxicity profile and caustic effects pose significant concerns for dermal applications, deeming it unsuitable for precision skincare.

emulsion stabilising pH adjuster

Science

Functions as a strong organic base (pKa of conjugate acid 10.75 at 25°C), effectively elevating the pH of a formulation. This property is crucial for achieving specific pH targets, with a 1% solution exhibiting a pH of approximately 10, and for maintaining the stability of oil-in-water emulsions.


Research

Insufficient-data confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

Triethylamine serves a clear functional role as a pH adjuster and emulsion stabilizer, meaning it is not an ingredient typically 'dusted' for questionable or sub-efficacious claims. However, its potent basicity and severe toxicity profile, including documented skin burns and eye damage, render it a significant safety concern. The lack of a determined safe maximum concentration for cosmetic use further underscores its unsuitability for precision skincare formulations.


The Formula

Solubility
Both
Optimal pH N/A
0 7 14

Stability

This strong base maintains stability under typical conditions but is extremely flammable and readily forms explosive mixtures with air. It must be isolated from strong acids, potent oxidizing agents, ketones, aldehydes, and halogenated hydrocarbons. Direct contact with certain plastics, rubbers, and coatings should also be avoided due to potential material degradation.

Conflicts

  • strong acids
  • strong oxidizing agents
  • ketones
  • aldehydes
  • halogenated hydrocarbons
  • certain plastics
  • certain rubbers
  • certain coatings

Safety

CIR Status
Not reviewed
Sensitization risk High

Triethylamine is classified as toxic if swallowed, in contact with skin, or if inhaled, causing severe skin burns and serious eye damage. Acute vapor exposure can induce eye irritation, corneal swelling, and halo vision in humans, in addition to irritating skin and mucous membranes. Chronic exposure has resulted in reversible corneal edema, respiratory and hematological issues, and ocular lesions in animal studies. A 70% solution applied to guinea pig skin produced severe irritation and extensive tissue necrosis. The EPA has not classified it for carcinogenicity. It is listed as a California Safe Cosmetics Program (CSCP) Reportable Ingredient due to documented neurotoxicity, ocular toxicity, and respiratory toxicity concerns, particularly when used as a fragrance or flavor component.


Your Skin

No Normal
No Dry
No Oily
No Sensitive
Irritancy High
Comedogenicity Unknown

Our Assessment

Avoid

Due to its severe toxicity, including caustic effects on skin and eyes, its classification as a California Safe Cosmetics Program Reportable Ingredient, and the absence of a determined safe maximum concentration for cosmetics, Triethylamine is incompatible with precision skincare formulations.


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