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TRICHLOROETHANE.

Avoid CAS 71-55-6 / SOLVENT

Trichloroethane, specifically 1,1,1-Trichloroethane, is a chlorinated solvent historically used in industrial applications, now largely prohibited due to its classification as an ozone-depleting substance. Despite a past safety assessment for cosmetic use, it is not currently utilized in skincare formulations.

Solvent

Science

As a solvent, Trichloroethane exerts a defatting action upon skin contact. This mechanism strips natural lipids from the epidermal barrier, potentially leading to significant irritation and dryness. While skin absorption occurs, inhalation represents a more prominent route of exposure.


Research

Low confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

The Formula

Solubility
Both
Optimal pH N/A
0 7 14

Stability

1,1,1-Trichloroethane is a colorless liquid prone to decomposition at high temperatures, emitting toxic chloride fumes. It reacts slowly with water to form hydrochloric acid. Formulations typically incorporate additives to inhibit its decomposition and prevent metal corrosion.

Conflicts

  • Chemically active metals (e.g., aluminum, magnesium and their alloys)
  • Strong oxidizers
  • Strong bases
  • Dinitrogen tetraoxide
  • Oxygen
  • Liquid oxygen
  • Sodium
  • Sodium-potassium alloys
  • Acetone
  • Zinc
  • Nitrates
  • Some forms of plastics, rubber, and coatings

Safety

CIR Status
Safe as used (but not currently used)
Sensitization risk High

The Cosmetic Ingredient Review (CIR) Expert Panel concluded 1,1,1-Trichloroethane to be safe as a cosmetic solvent; however, an industry survey indicates it is not used in cosmetics. Its production was banned globally by the Montreal Protocol in 1996 due to its classification as a Class I ozone-depleting substance by the U.S. EPA. The FDA deems its use in aerosol cosmetic products non-essential, making its practical application in cosmetics non-existent and largely prohibited due to significant environmental and regulatory concerns.


Your Skin

No Normal
No Dry
No Oily
No Sensitive
Irritancy High
Comedogenicity Unknown

Our Assessment

Avoid

Trichloroethane should be actively avoided in skincare due to its significant environmental impact as an ozone-depleting substance, its historical prohibition in many applications, and its high potential for skin irritation and dryness.


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