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Moumoujus

TRANS, TRANS-NONA-2,4-DIENAL.

Avoid CAS 5910-87-2 / PERFUMING

An aldehyde predominantly used as a perfuming agent, TRANS, TRANS-NONA-2,4-DIENAL delivers a distinctive fatty, green, and subtly citrusy aroma. However, its inclusion in precision skincare is highly problematic due to its classification as a potent skin sensitizer and irritant, with evidence suggesting potential cellular damage.

Summary

Perfuming

Science

Mechanism of Action

TRANS, TRANS-NONA-2,4-DIENAL functions primarily to impart specific olfactive notes, characterized by fatty, green, and citrus nuances. As an aldehyde, it can be reactive. While some exploratory research hints at possible antimicrobial and antioxidant properties, more compelling data indicates its capacity to induce oxidative DNA damage and provoke cell injury in human skin keratinocytes.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

This ingredient's primary role is perfuming, which is generally considered a non-essential additive in precision skincare formulations. Its presence is not attributed to being an overhyped active ingredient, but rather an ancillary component with significant safety liabilities.

The Formula

Formulation

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

As a reactive aldehyde, TRANS, TRANS-NONA-2,4-DIENAL exhibits light sensitivity. Optimal stability is maintained under tightly closed conditions and refrigeration, ideally at +4°C.

Conflicts

  • Prohibited as a fragrance ingredient by the International Fragrance Association (IFRA)

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk High

TRANS, TRANS-NONA-2,4-DIENAL carries a substantial risk for skin irritation, allergic reactions, and contact dermatitis. PubChem explicitly classifies it as both an irritant and a Skin Sensitizer (H317: May cause an allergic skin reaction, Skin Sens. 1). Furthermore, the International Fragrance Association (IFRA) mandates its prohibition as a fragrance ingredient. Due to these critical concerns, comprehensive patch testing is stringently recommended prior to any widespread use. Data regarding its topical application during pregnancy and breastfeeding are currently insufficient for safety assessment.

Your Skin

Skin Compatibility

No Normal
No Dry
Yes Oily
No Sensitive
Irritancy Moderate
Comedogenicity Low

Our Assessment

Verdict

Avoid

Considering its established role as a potent skin sensitizer and irritant, potential to induce oxidative DNA damage, and explicit prohibition by the IFRA for fragrance applications, TRANS, TRANS-NONA-2,4-DIENAL should be unequivocally avoided in skincare formulations due to its significant safety profile.

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