Science
Mechanism of Action
Trans-2-Hexenol functions solely as a perfuming agent, contributing a specific aroma to cosmetic formulations. No intrinsic therapeutic mechanisms or direct benefits for skin physiology have been identified in research data.
Research
Clinical Evidence
Low confidenceN/A
Transparency
Dusting Analysis
The Formula
Formulation
Stability
This ingredient is stable in perfumes and various functional bases, but it is a flammable liquid and vapor. For optimal stability, avoid prolonged exposure to light, heat, and air, storing it in a tightly closed container. It is soluble in alcohol.
Conflicts
- strong oxidizing agents
- strong acids
Safety
Safety Profile
The Research Institute for Fragrance Materials (RIFM) considers Trans-2-Hexenol not clastogenic and without genotoxic potential in the presence of S9 metabolic activation, with an adequate margin of exposure. However, it exhibited positive genotoxicity in assays without S9 activation. It is classified as an irritant to skin and eyes and possesses the potential to cause allergic skin reactions, thus patch testing is recommended. While generally recognized as safe (GRAS) by the FDA for food flavoring, it lacks specific FDA listing for cosmetic use, and the SCCS has not specifically reviewed this compound for cosmetic safety.
Your Skin
Skin Compatibility
Our Assessment
Verdict
While offering a distinct fresh aroma, Trans-2-Hexenol's classification as an irritant and potential allergen, coupled with a lack of direct skincare benefits, positions it as a questionable inclusion for precision skincare formulations.
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