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TRANEXAMOYL DIPEPTIDE-23.

Valuable / BLEACHING

TRANEXAMOYL DIPEPTIDE-23 is a sophisticated synthetic tripeptide engineered for precision skincare. It offers superior efficacy in combating various forms of hyperpigmentation, including melasma and dark spots, through a unique dual-action mechanism. This ingredient is also suitable for sensitive skin types, making it a versatile addition to targeted treatments.

Summary

Skin Brightening Hyperpigmentation Reduction Melanin Inhibition Anti-inflammatory Anti-allergic Bleaching

Science

Mechanism of Action

This advanced tripeptide operates via a dual-action pathway to effectively reduce melanin production. Firstly, it directly inhibits tyrosinase, a key enzyme essential for melanin synthesis, thereby preventing the formation of new pigment. Secondly, it downregulates the expression of MITF (microphthalmia-associated transcription factor), which is crucial for the differentiation and proliferation of melanocytes—the cells responsible for producing melanin. This comprehensive inhibition significantly diminishes hyperpigmentation. Its small molecular size ensures optimal skin permeability and an enhanced penetration rate, further boosting its efficacy. Additionally, it exhibits anti-inflammatory and anti-allergic properties.

Research

Clinical Evidence

Medium confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 Clinical observations indicate that Tranexamoyl Dipeptide-23 demonstrates superior skin whitening activity when compared to established brightening agents such as Arbutin and Ascorbyl Glucoside.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Unknown
Optimal pH N/A
0 7 14

Stability

The integration of a Tranexamic Acid (TXA) modification within Dipeptide-23 is designed to enhance its stability within cosmetic formulations, optimizing its long-term effectiveness.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Low

Cytotoxicity studies suggest that Tranexamoyl Dipeptide-23 is a safe ingredient for use in skincare formulations. While specific official reviews from regulatory bodies such as CIR, SCCS, or FDA are not yet available, its observed compatibility with sensitive skin further supports a favorable safety profile.

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

TRANEXAMOYL DIPEPTIDE-23 stands as a valuable ingredient for advanced skin brightening, leveraging a powerful dual mechanism to effectively reduce various forms of hyperpigmentation, all while maintaining excellent skin compatibility, especially for sensitive skin.

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