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TOSYLAMIDE.

Avoid CAS 70-55-3 / 88-19-7 / PLASTICISER

Tosylamide, chemically known as p-Toluenesulfonamide, primarily functions as a plasticizer and a component in film-forming resins. While its derivatives are commonly utilized in nail products, its direct application for active skin benefits lacks extensive documentation.

plasticizer film forming component in film-forming resins

Science

Tosylamide acts as a film-forming agent, creating a continuous protective layer on surfaces such as skin, hair, or nails. It concurrently serves as a plasticizer, enhancing the flexibility and smoothness of formulations and materials that might otherwise be brittle. For direct skin applications, specific active mechanisms of action beyond a general 'skin conditioning' role are not clearly elucidated.


Research

Low confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

Tosylamide's primary roles are as a precursor for resins or a plasticizer, not typically used in a manner prone to dusting.


The Formula

Solubility
Both
Optimal pH N/A
0 7 14

Safety

CIR Status
Not reviewed
Sensitization risk High

The Cosmetic Ingredient Review (CIR) Expert Panel has not specifically evaluated Tosylamide (p-Toluenesulfonamide) as a standalone ingredient for direct topical cosmetic use. While a related derivative, Tosylamide/Formaldehyde Resin, was deemed safe at up to 12% in nail product studies, another derivative, Ethyl Tosylamide, is recognized as a skin and strong eye irritant. Crucially, Tosylamide is listed in COSing Annex II and is banned for use in cosmetics within the European Union, indicating it is considered unsafe for such applications.


Your Skin

No Normal
No Dry
No Oily
No Sensitive
Irritancy High
Comedogenicity Unknown

Our Assessment

Avoid

Tosylamide is banned for cosmetic use in the European Union due to safety concerns and lacks documented active skin benefits for direct topical application, making its inclusion in precision skincare highly inadvisable.


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