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TOCOPHERYL LINOLEATE.

Valuable CAS 36148-84-2 / ANTIOXIDANT, SKIN CONDITIONING, SKIN PROTECTING

A highly stable ester of Vitamin E and linoleic acid, Tocopheryl Linoleate functions as a provitamin, actively transforming within the skin to deliver potent antioxidant and skin-conditioning benefits. It significantly boosts hydration and reinforces the skin's natural barrier function.

Summary

Antioxidant Skin-Conditioning Agent Humectant Collagen Booster Anti-inflammatory

Science

Mechanism of Action

This compound is an ester comprising linoleic acid (an omega-6 fatty acid) and tocopherol (Vitamin E). Upon cutaneous application, it metabolizes into active Vitamin E, acting as a powerful antioxidant that neutralizes free radicals generated by environmental stressors like UV radiation and pollution. This protects cellular membranes from oxidative damage and premature aging. Concurrently, it operates as an effective skin conditioning agent, optimizing the stratum corneum's moisture retention, refining overall skin texture, and stimulating collagen synthesis. The linoleate component further contributes anti-inflammatory properties.

Research

Clinical Evidence

Medium confidence
Effective range 2–2%
Optimal

2%

Key findings

  1. 01 A 2% concentration increased surface skin water retention by 12% after 7 hours and decreased TransEpidermal Water Loss (TEWL) by 30% after 5 hours when compared to glycerin, and by 27% compared to placebo. (Based on corneometry and tewameter tests on 6 volunteers)
  2. 02 In a 28-day study with twice-daily application, 82% of panelists reported immediate skin moisturization, with 68% experiencing sustained all-day hydration. Furthermore, 73% noted smoother skin, and 68% observed immediately more supple and softer skin. (Self-assessment test on 22 women, aged 40-60)

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Oil
Optimal pH 1 – 14
0 7 14

Stability

Its ester structure confers superior stability to Vitamin E within cosmetic formulations, facilitating a gradual and sustained release of the active compound into the skin for prolonged efficacy.

Safety

Safety Profile

CIR Status
Safe as used
Max tested
2%
Sensitization risk Low

The CIR Expert Panel has deemed Tocopheryl Linoleate safe for use in cosmetic and personal care products. Incidences of positive patch-tests previously reported were attributed to contaminants or metabolites rather than the ingredient itself. Its parent compound, Tocopherol (Vitamin E), holds Generally Recognized As Safe (GRAS) status for food use by the FDA.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Tocopheryl Linoleate is a valuable provitamin E offering robust antioxidant protection, significant hydration, and skin conditioning benefits across all skin types.

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