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Moumoujus

TOCOPHERYL ACETATE.

Valuable CAS 7695-91-2 / 58-95-7 / ANTIOXIDANT, SKIN CONDITIONING

A stable, esterified form of Vitamin E, Tocopheryl Acetate functions as a robust antioxidant and skin-conditioning agent. It fortifies the skin's natural defenses against environmental aggressors while promoting hydration and overall skin health.

Summary

antioxidant skin conditioning

Science

Mechanism of Action

Tocopheryl Acetate works by neutralizing free radicals, thereby protecting the skin from oxidative stress and damage caused by UV exposure and pollution. Upon topical application, approximately 5% is converted into active free tocopherol within living skin cells, supporting the skin's natural lipid barrier, enhancing hydration, and reducing transepidermal water loss. It also exhibits anti-inflammatory properties by inhibiting specific cytokines and enzymes, contributing to a smoother, soothed complexion and aiding in the repair of micro-damage.

Research

Clinical Evidence

High confidence
Effective range 0.1–5%
Optimal

0.5%

Key findings

  1. 01 Demonstrated effective and safe, especially for sensitive skin, with 0.5% identified as optimal for therapeutic antioxidant benefits.
  2. 02 Proven to elevate Vitamin E levels within the skin.
  3. 03 Used in studies for photo-protective effects, though found to be less potent than free alpha-tocopherol in preventing DNA photodamage at this concentration.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

Highly stable, offering resistance to oxidation, heat, air, and light, which enhances product freshness and longevity. However, it is susceptible to saponification in the presence of alkalis and reacts with strong oxidizing agents.

Synergies

  • Vitamin C

Conflicts

  • alkalis
  • strong oxidizing agents

Safety

Safety Profile

CIR Status
Safe as used
Sensitization risk Low

The Cosmetic Ingredient Review (CIR) Expert Panel affirms its safety in cosmetics. Initial concerns regarding irritation were resolved, confirming it is neither an irritant nor a sensitizer. The SCCS also concluded it poses no consumer health threat, proposing no usage restrictions. The FDA recognizes tocopherols, including Tocopheryl Acetate, as Generally Recognized As Safe (GRAS) for food use.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Valuable

Tocopheryl Acetate is a valuable ingredient, providing stable antioxidant protection and comprehensive skin conditioning benefits across all skin types with a low risk of irritation or sensitization.

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