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Moumoujus

THUJOPSIS DOLABRATA WOOD OIL.

Questionable CAS 91722-39-3 / FRAGRANCE, PERFUMING

Thujopsis Dolabrata Wood Oil is a potent botanical essential oil recognized for its antimicrobial, anti-inflammatory, and antiseptic properties. It works to support skin health by combating harmful microbes, soothing irritation, and reducing redness and inflammation. Its distinct actions make it a candidate for targeted skin concerns.

Summary

Antimicrobial Anti-inflammatory Antifungal Antiseptic Soothing agent Fragrance component

Science

Mechanism of Action

This wood oil exerts its beneficial effects through its inherent antimicrobial, anti-inflammatory, antifungal, and antiseptic actions, which collectively combat pathogenic microbes and prevent infections on the skin. Specifically, components of the essential oil have been demonstrated to inhibit the production of IgE and histamine, thereby reducing IgE-mediated degranulation. This mechanism is crucial in mitigating atopic dermatitis-like skin lesions and calming irritated skin.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 In an in vivo/in vitro mouse model, Thujopsis Dolabrata Wood Oil effectively reduced atopic dermatitis-like skin lesions. This reduction was mediated by inhibiting IgE and histamine production and subsequent IgE-mediated degranulation. The oil also dose-dependently inhibited beta-hexosaminidase release from rat basophilic leukemia RBL 2H3 cells.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

To maintain optimal purity and efficacy, store the pure essential oil in brown glass bottles, ensuring it is upright with the cap firmly secured. It should be kept out of direct sunlight in a cool, dry environment to maximize its shelf life.

Conflicts

  • Undiluted application on skin
  • Application on damaged or inflamed skin
  • Application near or in eyes
  • Use during pregnancy
  • Use during breastfeeding
  • Higher doses (potential reproductive toxicity)

Safety

Safety Profile

CIR Status
Not reviewed
Max tested
7%
Pregnancy
Caution
Sensitization risk High

Thujopsis Dolabrata Wood Oil is classified as an irritant (R 36/38), indicating its potential to irritate both skin and eyes. Topical application must always involve dilution, and direct use on damaged or inflamed skin, or near the eyes, is strictly contraindicated. Patch testing is strongly recommended prior to initial use. Given potential reproductive toxicity at elevated doses, this essential oil should be avoided during pregnancy and breastfeeding. The cited maximum concentration of 7.0% is recommended by RIFM for fragrance concentrates.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy High
Comedogenicity Unknown

Our Assessment

Verdict

Questionable

While Thujopsis Dolabrata Wood Oil demonstrates promising antimicrobial and anti-inflammatory benefits, particularly in preclinical models for atopic dermatitis, its classification as a significant irritant and contraindications for vulnerable populations like pregnant and breastfeeding individuals necessitate extreme caution and limit its suitability for precision skincare formulations.

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