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Moumoujus

THUJA OCCIDENTALIS LEAF.

Questionable CAS 90131-58-1 / SKIN CONDITIONING

Derived from the coniferous tree, Thuja Occidentalis Leaf is recognized for its traditional uses in addressing various skin concerns. It possesses antioxidant, anti-inflammatory, and broad-spectrum antimicrobial properties, contributing to skin conditioning and protection against environmental stressors. Its complex phytochemistry underpins its diverse actions on the skin.

Summary

antioxidant anti-inflammatory antibacterial antifungal antiviral skin conditioning antiseptic bleaching hair conditioning perfuming

Science

Mechanism of Action

The efficacy of Thuja Occidentalis Leaf on the skin is attributed to its rich composition of bioactive constituents, including essential oils, coumarins, flavonoids, tannins, and proanthocyanidines. These compounds collectively exert antioxidant effects, mitigating oxidative stress and DNA damage, alongside anti-inflammatory, antibacterial, antifungal, and antiviral actions. This multifaceted mechanism provides both conditioning and antiseptic benefits to the skin.

Research

Clinical Evidence

Medium confidence
Effective range 10–20%
Optimal

N/A

Key findings

  1. 01 Historically employed in herbal medicine for its ability to aid in the removal of warts and alleviate fungal infections on hands and feet, with typical concentrations ranging from 2.5% to 5% dry extract or at least 50% tincture (both equivalent to 10-20% crude dried herb tops).
  2. 02 Demonstrated successful treatment of verruca vulgaris in a case study involving a renal allograft recipient, highlighting its specific antiviral potential.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Stability

Formulated ointments containing Thuja Occidentalis extract exhibit good consistency, spreadability, homogeneity, and pH stability, maintaining visual appearance, nature, viscosity, and aroma over research periods without phase separation.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Moderate

The SCCS has approved Thuja Occidentalis Leaf Extract for cosmetic use with significant restrictions (EC Cosmetics Regulation III/119), primarily due to the toxic thujone content (alpha and beta). Thujone in the essential oil is limited to 0.5%, with dried twigs containing approximately 0.76% thujone. The FDA has not extensively reviewed this ingredient for cosmetic use. High use restrictions are noted by EWG, advising against facial or genital application due to potential irritation. Oral overdose can lead to severe metabolic disturbances and irritant effects on internal organs.

Your Skin

Skin Compatibility

Yes Normal
No Dry
Yes Oily
No Sensitive
Irritancy Medium
Comedogenicity Unknown

Our Assessment

Verdict

Questionable

While offering targeted antimicrobial and antioxidant benefits, Thuja Occidentalis Leaf's cosmetic use is subject to stringent regulatory limits due to potential thujone toxicity and reported medium irritancy, mandating cautious and professionally guided formulation.

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