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THREITOL.

Questionable CAS 2418-52-2 / 7493-90-5 / HUMECTANT

Threitol, a polyol sugar alcohol, functions primarily as a humectant, adept at attracting and retaining moisture within the skin. While it contributes to general skin protection, its inclusion in formulations warrants caution due to its potential for irritation.

Humectant Skin-protective agent

Science

As a polyol, Threitol operates as a humectant, drawing and retaining water in the skin to enhance hydration. Additionally, it is inferred to possess properties that contribute to overall skin protection.


Research

Low confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

The Formula

Solubility
Water
Optimal pH N/A
0 7 14

Stability

The compound is hygroscopic, meaning it readily absorbs moisture from the air.

Conflicts

  • Strong oxidizing agents (e.g., nitrates, oxidizing acids, chlorine bleaches, pool chlorine)

Safety

CIR Status
Not reviewed
Sensitization risk Moderate

While generally exhibiting low toxicity, the D-Threitol isomer is associated with GHS hazard statements indicating potential for skin irritation (H315) and serious eye irritation (H319). It has the capacity to cause skin inflammation in certain individuals and may worsen existing dermatitis conditions. Its safety for cosmetic use has not been reviewed by the Cosmetic Ingredient Review (CIR).


Your Skin

No Normal
Yes Dry
No Oily
No Sensitive
Irritancy Medium
Comedogenicity Unknown

Our Assessment

Questionable

Despite its humectant properties beneficial for dry skin, the 'medium' irritancy rating, potential to cause skin inflammation and exacerbate dermatitis, coupled with an unreviewed CIR safety status, positions Threitol as a questionable ingredient for precision skincare.


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