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Moumoujus

THIAMINE/YEAST POLYPEPTIDE.

Insufficient Data CAS - / SKIN CONDITIONING

THIAMINE/YEAST POLYPEPTIDE integrates Vitamin B1, a vital nutrient for cellular energy and antioxidant defense, with yeast-derived polypeptides known for their skin conditioning, protective, and hydrating properties. This synergistic complex is designed to promote cellular vitality, support DNA repair, and potentially enhance skin elasticity and barrier function.

Summary

Skin conditioning Antioxidant Skin protectant Humectant Collagen stimulating

Science

Mechanism of Action

This advanced complex delivers the multifaceted benefits of Thiamine (Vitamin B1) and specialized yeast polypeptides. Thiamine is crucial for cutaneous cellular health, participating in glucose metabolism, DNA repair mechanisms, and providing significant antioxidant defense against oxidative stress. Concurrently, yeast polypeptides function as effective skin-conditioning agents, humectants, and protectants. Research indicates certain yeast-derived peptides can stimulate endogenous collagen synthesis, improve skin elasticity, and mitigate the appearance of fine lines by inhibiting collagenase activity. The yeast components in this complex are also recognized for their ability to bind thiamine, suggesting an optimized delivery system for enhanced cellular vitality and antioxidant protection within the skin matrix.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Stability

Thiamine exhibits inherent instability in alkaline environments, favoring acidic pH values (e.g., pH 3 demonstrates significantly greater stability than pH 6). It is also susceptible to degradation from exposure to heat, light, and sulfites. While yeast components may confer some protective or binding capabilities for thiamine, the precise optimal pH range for the stability of the integral THIAMINE/YEAST POLYPEPTIDE complex remains to be explicitly defined. It is noteworthy that thiamine-binding proteins from certain sources have demonstrated optimal activity at neutral pH, such as pH 8.6 in specific instances.

Conflicts

  • alkaline conditions
  • heat
  • light
  • sulfites

Safety

Safety Profile

CIR Status
Insufficient data
Sensitization risk Low

The Cosmetic Ingredient Review (CIR) Expert Panel concluded that while many yeast-derived ingredients are safe under specific conditions (derived from species with dermal sensitization and food use status), data for this specific complex, THIAMINE/YEAST POLYPEPTIDE, is currently insufficient for a safety determination. However, its individual components are widely recognized: the FDA affirms Saccharomyces cerevisiae (a common yeast) as Generally Recognized As Safe (GRAS) at levels up to 5% in food, and Thiamine (Vitamin B1) is an essential medicine listed by the WHO, indicating general safety.

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
No Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Insufficient Data

This ingredient offers a compelling blend of cellular vitality and skin conditioning benefits, though specific clinical data for the complex and a full CIR safety determination are currently limited.

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