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TETRAPEPTIDE-46.

Insufficient Data / SKIN CONDITIONING

TETRAPEPTIDE-46 is a synthetic peptide composed of a four-amino acid sequence. While specific in-depth research for this particular tetrapeptide is limited, peptides of this nature are generally investigated for their potential to influence cellular processes within the skin.

Collagen Stimulation Skin Elasticity Improvement

Science

Broadly, peptides are understood to act as signaling molecules within the skin, potentially initiating pathways that contribute to beneficial dermatological outcomes such as stimulating collagen synthesis and enhancing elastin production. These actions can collectively support improvements in skin firmness and overall elasticity.


Research

Low confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

Specific clinical efficacy data for TETRAPEPTIDE-46 is currently unavailable, preventing the establishment of an evidence-based dusting threshold for this particular ingredient.


The Formula

Solubility
Unknown
Optimal pH N/A
0 7 14

Stability

The precise optimal pH range and specific stability characteristics for TETRAPEPTIDE-46 are not explicitly documented. However, general peptide stability and solubility are highly dependent on pH. Formulating in buffered aqueous solutions with a pH between 3 and 5 is typically recommended for peptides to minimize degradation mechanisms such as deamidation and oxidation, and to provide protection for disulfide bridges. Peptides generally require careful formulation to maintain their chemical and physical stability, avoiding self-association and aggregation, and should be protected from light and elevated temperatures.


Safety

CIR Status
Not reviewed
Sensitization risk Unknown

TETRAPEPTIDE-46 has not undergone specific safety assessments by regulatory bodies such as CIR (Cosmetic Ingredient Review), SCCS (Scientific Committee on Consumer Safety), or the FDA. While cosmetic peptide ingredients are commonly used at concentrations between 1 ppm and 30 ppm, with customary concentrations often less than 10 ppm, ingredient-specific toxicological data for TETRAPEPTIDE-46 is currently unavailable.


Your Skin

No Normal
No Dry
No Oily
No Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Insufficient Data

The current lack of specific clinical efficacy data, detailed safety assessments, and precise formulation guidance for TETRAPEPTIDE-46 renders its specific benefits and optimal application in skincare largely undetermined.


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References