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Moumoujus

TETRAMETHYLOLGLYCOLURIL.

Avoid CAS 5395-50-6 / ANTIMICROBIAL

Tetramethylolglycoluril functions primarily as an antimicrobial agent, designed to suppress the growth and replication of bacteria, fungi, and viruses. While effective in rendering the stratum corneum temporarily bactericidal and fungicidal, its significant potential for causing allergic skin reactions raises substantial safety concerns for topical application.

Summary

antimicrobial preservative

Science

Mechanism of Action

This compound exerts its antimicrobial action by inhibiting the proliferation of a wide range of microorganisms, including various bacteria, fungi, and viruses. It achieves this by imparting temporary bactericidal and fungicidal properties to the stratum corneum.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Unknown
Optimal pH N/A
0 7 14

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk High

Tetramethylolglycoluril carries a GHS 'Warning' signal word. It is classified as Skin Sens. 1, with an H317 statement indicating it 'May cause an allergic skin reaction,' a risk reported in 97.6% of cases. Additionally, it carries an H411 statement, meaning it is 'Toxic to aquatic life with long lasting effects,' reported in 36.7% of cases. The New Zealand Environmental Protection Authority notes that it lacks individual approval and is only permitted as a component within a product covered by a group standard, not as a standalone chemical.

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
No Sensitive
Irritancy High
Comedogenicity Unknown

Our Assessment

Verdict

Avoid

Due to an exceptionally high reported incidence of allergic skin reactions (97.6%) and its classification as a strong skin sensitizer, Tetramethylolglycoluril is deemed unsuitable and should be avoided in precision skincare formulations.

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